Malte Lenders Selected Research

Galactosidases

1/2022	Treatment of Fabry Disease management with migalastat-outcome from a prospective 24 months observational multicenter study (FAMOUS).
11/2021	Mechanisms of Neutralizing Anti-drug Antibody Formation and Clinical Relevance on Therapeutic Efficacy of Enzyme Replacement Therapies in Fabry Disease.
10/2021	α-Galactosidase a Deficiency in Fabry Disease Leads to Extensive Dysregulated Cellular Signaling Pathways in Human Podocytes.
4/2021	Fabry Disease: The Current Treatment Landscape.
3/2021	Treatment of fabry disease with migalastat-outcome from a prospective 24 months observational multicenter study (FAMOUS).
3/2021	Generation and Characterization of a Polyclonal Human Reference Antibody to Measure Anti-Drug Antibody Titers in Patients with Fabry Disease.
1/2021	Precision medicine in Fabry disease.
1/2021	Endothelial Dysfunction in Fabry Disease Is Related to Glycocalyx Degradation.
9/2020	Detailed epitope mapping of neutralizing anti-drug antibodies against recombinant α-galactosidase A in patients with Fabry disease.
1/2020	Treatment of Fabry's Disease With Migalastat: Outcome From a Prospective Observational Multicenter Study (FAMOUS).

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Malte Lenders Research Topics

Disease

30	Fabry Disease (Fabry's Disease) 01/2022 - 01/2013
5	Stroke (Strokes) 11/2021 - 11/2014
4	Body Weight (Weight, Body) 11/2021 - 04/2014
4	Disease Progression 11/2021 - 12/2018
4	Lysosomal Storage Diseases (Lysosomal Storage Disease) 04/2021 - 01/2020
3	Cardiomyopathies (Cardiomyopathy) 11/2021 - 01/2021
3	Cardiac Arrhythmias (Arrythmia) 11/2021 - 01/2021
3	Renal Insufficiency (Renal Failure) 11/2021 - 01/2021
2	Heart Failure 10/2017 - 12/2014
1	Dysbiosis 01/2022
1	Chronic Renal Insufficiency 01/2021
1	Leukocytosis (Pleocytosis) 01/2020
1	Liver Diseases (Liver Disease) 01/2020
1	Hepatolenticular Degeneration (Wilson's Disease) 01/2020
1	Pathologic Constriction (Stenosis) 01/2019
1	Albuminuria 01/2019
1	Neoplasms (Cancer) 01/2018
1	Breast Neoplasms (Breast Cancer) 01/2018
1	Cerebral Infarction 10/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 10/2017
1	Neuroblastoma 01/2017
1	Transient Ischemic Attack 01/2016
1	Mitral Valve Insufficiency (Mitral Regurgitation) 12/2014
1	Small Fiber Neuropathy 11/2014
1	Neurologic Manifestations (Neurological Manifestations) 11/2014
1	Ischemic Stroke 11/2014
1	Diarrhea 04/2014
1	Chronic Pain 04/2014
1	Pain (Aches) 04/2014

Drug/Important Bio-Agent (IBA)

14	GalactosidasesIBA 01/2022 - 01/2018
8	AntibodiesIBA 11/2021 - 01/2018
7	EnzymesIBA 01/2022 - 01/2020
7	globotriaosylceramide (globotriosylceramide)IBA 01/2022 - 12/2018
7	migalastatIBA 01/2022 - 01/2019
7	Pharmaceutical PreparationsIBA 11/2021 - 01/2018
4	agalsidase alfaIBA 04/2021 - 04/2014
4	alpha-Galactosidase (Beano)IBA 10/2020 - 11/2014
3	agalsidase beta FDA Link 04/2021 - 04/2014
3	GlycosphingolipidsIBA 04/2021 - 01/2013
3	globotriaosyl lysosphingolipidIBA 01/2021 - 01/2016
1	PrebioticsIBA 01/2022
1	EpitopesIBA 09/2020
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	Oligoclonal BandsIBA 01/2020
1	CopperIBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	HydrolasesIBA 10/2019
1	MicroRNAs (MicroRNA)IBA 10/2019
1	CreatinineIBA 01/2019
1	Transcription Factors (Transcription Factor)IBA 01/2018
1	Annexin A5IBA 01/2018
1	Neutralizing AntibodiesIBA 01/2018
1	SaltsIBA 10/2017
1	MethyltransferasesIBA 01/2017
1	factor V LeidenIBA 03/2015
1	Genetic Markers (Genetic Marker)IBA 12/2014

Therapy/Procedure

14	Enzyme Replacement Therapy 11/2021 - 04/2014
4	Therapeutics 01/2022 - 01/2019
2	Drug Tapering 03/2016 - 04/2014
1	Precision Medicine 01/2021
1	Cardiac Resynchronization Therapy 12/2014